Single Source: HeartShare 2.0: Refining Heart Failure Subtypes and Treatment Targets for Personalized Clinical Trials - Data Translation Center (U54 Clinical Trial Optional)

National Institutes of Health · HHS

CFDA Numbers

93.837

Award Ceiling

—

Award Floor

—

Expected Awards

—

Close Date

Jul 9, 2026

Section I

How to Apply

View on grants_gov ↗

Program Contact

Division of Cardiovascular Sciences, HeartShare Team<br/>nhlbiheartshare@mail.nih.gov
nhlbiheartshare@mail.nih.gov

Section II

Eligibility

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibilityThis is a non-competitive funding opportunity intended, if the peer-reviewed application is meritorious, to fund a single award. Only the following applicant is eligible to apply for this single source funding: Northwestern University.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Eligible Applicant Types

00, 01, 02, 04, 05, 06, 07, 08, 11, 12, 13, 20, 22, 23, 25

Section III

Description

This is a Notice of Funding Opportunity (NOFO) for a Single Source that will invites an application from an eligible organization to apply. Please see Section III. Eligibility for additional information. The NHLBI is announcing its intent to issue a single source cooperative agreement to Northwestern University. This NOFO solicits a renewal of the Data Translation Center for an ongoing NHLBI phenomics program, HeartShare, to coordinate the overall project, continue to oversee enrollment of a cohort of patients with heart failure with preserved ejection fraction (HFpEF), curate and analyze prospective deep phenotyping data, and support planning, implementation, and data analysis for clinical trials. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered.Companion NOFO RFA-HL-27-008 will support Clinical Centers for recruitment and follow-up of heart failure patients and a Clinical Trial Center for new clinical trial activities.

Section IV

Key Dates

Posted: May 19, 2026
Closes: Jul 9, 2026
Archive: Sep 7, 2026