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University of Ky
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Lexington, KY
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$38K
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To understand how maladaptive changes to the integrated stress response pathway alter the force generating ability of human heart cells and determine if pharmacological manipulation can rescue cardiomyocyte function.
|
2022
|
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John Hopkins University
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Baltimore, MD
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$38K
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To use tumor organoid and mouse models to determine how loss of claudin proteins impacts tumor invasion and metastasis.
|
2022
|
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Salk Institute for Bio Studies
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La Jolla, CA
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$50K
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To use innovative cell biology techniques coupled with genomics to investigate the role of mitochondrial-derived vesicles in cancer cell metabolism.
|
2022
|
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Whitehead Institute for Biomed
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Cambridge, MA
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$50K
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To uncover the set of cell-surface proteins that mediate essential interactions between pdac cells and their microenvironment.
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2022
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John Hopkins University
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Baltimore, MD
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$50K
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To investigate how the colon microbiota and host genetics intersect to alter responsiveness to immunotherapy in colorectal cancer.
|
2022
|
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Ma Institute of Technology
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Cambridge, MA
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$150K
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To enhance nanoparticle accumulation in desired cell types to develop more effective and safer targeted nanotherapies.
|
2022
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Institute for Cancer Research
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Philadelphia, PA
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$38K
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To investigate the role of brg1-dependent epigenetic regulation on pdac fibroblast pro-tumorigenic functions.
|
2022
|
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Weill Med College of Cornell U
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New York, NY
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$150K
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To identify regulators of lineage reversion that impact resistance to wnt-targeted therapies in colorectal cancer.
|
2022
|
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University of Guelph
|
|
$100K
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To identify combinations of commercial bacterial isolates that suppress klebsiella pneumoniae in the colon and the underlying cooperative mechanisms of this activity.
|
2022
|
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Ma Institute of Technology
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Cambridge, MA
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$38K
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To develop a high-throughput single-cell gro-seq assay to examine the tumor microenvironment established by mutant-p53 and decipher the gene regulatory networks underlying pdac's intrasigence to immunotherapies.
|
2022
|
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University of Md Baltimore Foundati
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Baltimore, MD
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$75K
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To investigate the regulation of treg lymphatic tumor migration and the interaction among tregs, lymphatic endothelial cells, and tumors to develop strategies of delivering targeted therapies locally instead of sySTEMically.
|
2022
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Dana-Farber Cancer Institute
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Boston, MA
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$100K
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To map the transcriptional and protein changes induced by lactate and identify the mechanisms that cause nk suppression, on both nk and tumor cells, using high-throughput and unbiased approaches.
|
2022
|
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John Hopkins University
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Baltimore, MD
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$5K
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To investigate how the colon microbiota and host genetics intersect to alter responsiveness to immunotherapy in colorectal cancer.
|
2022
|
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Rockefeller University
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New York, NY
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$75K
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To investigate the role of trna-derived fragments and the genes they regulate in breast cancer progression and metastasis.
|
2022
|
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Institute for Cancer Research
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Philadelphia, PA
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$5K
|
To investigate the role of brg1-dependent epigenetic regulation on pdac fibroblast pro-tumorigenic functions.
|
2022
|
|
University of Ca Santa Barbara
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Santa Barbara, CA
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$38K
|
To understand how maladaptive changes to the integrated stress response pathway alter the force generating ability of human heart cells and determine if pharmacological manipulation can rescue cardiomyocyte function.
|
2022
|
|
Ca Institute of Technology
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Pasadena, CA
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$80K
|
To develop interpretable machine learning methods that link spatial phenotypes in imaging data of solid tumors with patient outcomes.
|
2022
|
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Univeristy of Ca San Francisco
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San Francisco, CA
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$75K
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To develop a small molecule that stabilizes mutant p53 in cancer and further elaborate this compound with the ability to INCrease dna binding of bound p53.
|
2022
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